Antipsychotic medicines: what you need to know
Antipsychotic medicines help control symptoms like hallucinations, delusions, severe agitation and disorganized thinking. People use them for conditions such as schizophrenia, bipolar disorder with psychotic features, and sometimes severe depression or agitation. If you or someone you care for is starting an antipsychotic, this page gives clear, practical points to keep in mind.
How antipsychotics work
Most antipsychotics change brain chemistry to reduce psychosis. Older "typical" drugs mainly block dopamine and can be effective but often cause movement side effects called extrapyramidal symptoms. Newer "atypical" drugs target both dopamine and serotonin and tend to cause fewer movement problems, though they can bring metabolic issues like weight gain, raised blood sugar and cholesterol. Every drug is different — risperidone, olanzapine, quetiapine, and aripiprazole are common names you might hear.
Safe use and common side effects
Start low, go slow is a useful rule. Doctors usually begin at a low dose and adjust based on benefit and side effects. Watch for drowsiness, dry mouth, constipation, blurred vision, and weight changes. Serious but rarer risks include movement disorders, metabolic changes, and a small risk of low blood pressure or heart rhythm changes. Always report sudden stiffness, tremors, fever, or a high heart rate — those can signal urgent problems.
Practical tips: take pills at the same time each day, use a pillbox or phone alarm, and don’t stop a medication suddenly without checking with the prescriber. Keep a simple symptom diary for a few weeks to track benefits and side effects — a short list helps your clinician adjust treatment faster.
Before starting, tell your doctor about other drugs, supplements, and medical history. Antipsychotics interact with many medicines, including some blood pressure drugs, antidepressants, and over-the-counter cold remedies. Also mention diabetes, heart issues, liver problems, or pregnancy plans — these affect choice and dose.
Monitoring usually includes weight, blood pressure, fasting blood sugar and lipids, and sometimes heart tests. For long-term users, periodic reviews help decide if the dose can be reduced or if a switch is safer.
If you’re worried about side effects or cost, ask about alternatives and support options. There are alternative antipsychotics and non-drug treatments like therapy, social support, and targeted rehab that can help alongside medication. If you find your medication causes troubling effects, don’t quit alone — call your prescriber and ask for a plan.
This tag page collects articles on antipsychotic choices, comparisons, and safety tips. Browse posts to compare drugs, read patient-friendly guides, and find practical checklists to bring to appointments.
Changing antipsychotics takes time. Tapers, cross-tapers, and slow switches reduce withdrawal and relapse. Ask for written plans that list target doses, expected timelines, and side effects to watch for. Family or carers should know warning signs and emergency contacts. If cost is an issue, ask about generics, patient assistance, or community mental health services that can help with prescriptions and monitoring.
Keep all medical notes, medication lists, and lab results in one place and share them with any new clinician or pharmacist you see today.