The Orange Book database is the FDA's official list of approved drug products with patent and therapeutic equivalence data. It drives generic drug competition, lowers prescription costs, and is used daily by pharmacists, manufacturers, and patients.
Generic combination drugs may have the same active ingredients as brand names, but differences in inactive ingredients can affect how they work-especially for sensitive patients. Learn when substitutions are safe and when to push back.
Switching to generic medications is safe for most people, but some may notice changes in how they feel. Learn which drugs need extra monitoring, what symptoms to watch for, and how to track your health after the switch.
